Search results for " Frankincense"
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Natural resins: chemical constituents and medicinal uses
2011
Plants and their exudates are used worldwide for the treatment of several diseases and novel drugs continue to be developed through phytochemical research. There are more than 20,000 species of high vegetables, used in traditional medicines that are sources of potential new drugs. Following the modern medicine and drug research advancing, chemically synthesized drugs have replaced plants as the source of most medicinal agents in industrialized countries. However, in developing countries, the majority of the world’s population cannot afford pharmaceutical drugs and use their own plant based indigenous medicines. Several exudates from plants are well-known in folk medicine since ancient time,…
Molecular Determinants of the Response of Tumor Cells to Boswellic Acids
2011
Frankincense (Boswellia serrata, B. carterii) is used as traditional remedy to treat inflammatory diseases. The molecular effects of the active ingredients, the boswellic acids, on the immune system have previously been studied and verified in several clinical studies. Boswellic acids also inhibit cancer cell growth in vitro and in vivo. The molecular basis of the cytotoxicity of boswellic acids is, however, not fully understood as yet. By mRNA-based microarray, COMPARE, and hierarchical cluster analyses, we identified a panel of genes from diverse functional groups, which were significantly associated with sensitivity or resistance of a- or b-boswellic acids, such as transcription factors,…